Cannabinol (CBN): The Next High-Value Cannabinoid You Need to Know About in 2024

Cannabinol (CBN) is emerging as a major contender as the next high-value cannabinoid, thanks to its unique properties and potential health benefits. As interest in cannabinoids continues to grow, CBN is capturing the spotlight for its potential to aid in sleep, pain relief, and neuroprotection, making it a hot topic in both scientific research and commercial markets.

Cannabinol (CBN) is a mildly psychoactive cannabinoid found in cannabis plants. Here are the key points about CBN:

  • CBN is formed through the degradation and oxidation of tetrahydrocannabinol (THC), the primary psychoactive compound in cannabis.[1] As cannabis ages, THC breaks down into CBN.
  • CBN acts as a partial agonist at both the CB1 and CB2 cannabinoid receptors, interacting with the endocannabinoid system.[1] However, its affinity for these receptors is much lower than THC, making it only mildly psychoactive at higher doses.[1]
  • Potential benefits of CBN include:
  • Sleep aid and sedative effects, though more research is needed.[3][4]
  • Pain relief, especially when combined with CBD.[2]
  • Potential neuroprotective properties that may help delay diseases like ALS, though limited evidence.[2]
  • CBN is not currently scheduled under international drug control treaties, but its legal status varies. In the U.S., it is federally legal if derived from hemp with less than 0.3% THC.[1]
  • CBN is available in products like oils, tinctures, capsules, and vape pens, though not as widely available as CBD products.[2][4] More research is still needed on optimal dosages and effects.

Benefits of Cannabinol (CBN)

CBN, or Cannabinol, offers several potential health benefits that are attracting attention. Though research is still in its early stages, here’s what we know so far:

Improved Sleep

CBN is often touted as a sleep aid. Users report feeling more relaxed and finding it easier to fall asleep after using CBN. Some say it helps them stay asleep longer, too.

Pain Relief

CBN may help with pain relief. Some studies suggest it can reduce inflammation, making it potentially useful for conditions like arthritis. Users sometimes compare its effects to mild analgesics.

Appetite Stimulation

Like THC, CBN may stimulate appetite. This can be beneficial for people struggling with appetite loss due to medical conditions or treatments like chemotherapy.

Antibacterial Properties

CBN shows promise as an antibacterial agent. Early research indicates it could be effective against certain strains of bacteria, including MRSA, which is resistant to many antibiotics.

Neuroprotective Effects

CBN may offer neuroprotective benefits. Some studies suggest it could delay the onset of conditions like ALS. This makes it a subject of interest for researchers focusing on neurodegenerative diseases.

Glaucoma Relief

CBN might help reduce intraocular pressure, making it potentially useful for glaucoma patients. Lowering eye pressure can slow the progression of this eye disease.


CBN’s anti-inflammatory properties make it a candidate for treating conditions like Crohn’s disease and other inflammatory bowel diseases. It might also help with general inflammation and swelling.

Summary of Potential Benefits

Improved SleepHelps with relaxation and sleep initiation
Pain ReliefReduces inflammation and acts as a mild analgesic
Appetite StimulationStimulates appetite, useful for those undergoing treatments like chemotherapy
AntibacterialEffective against certain bacteria, including antibiotic-resistant strains
NeuroprotectiveCould delay the onset of neurodegenerative diseases
Glaucoma ReliefLowers intraocular pressure, beneficial for glaucoma patients
Anti-InflammatoryUseful for treating inflammatory conditions and general swelling

CBN’s potential benefits make it an exciting focus of ongoing research. As studies continue, we may discover even more uses for this fascinating cannabinoid.

Medical Applications

CBN is gaining attention for its potential medical benefits. Research is still in its early stages, but initial findings are promising. Here’s a look at some of the key medical applications of CBN:

Sleep Aid

CBN is often touted as a powerful sleep aid. Early studies suggest it may help improve sleep quality and duration. Insomniacs might find relief with CBN, making it a potential alternative to traditional sleep medications.

Pain Relief

CBN shows potential in pain management. It might work well for chronic pain conditions. Unlike THC, CBN provides pain relief without the psychoactive effects.


CBN may reduce inflammation. This makes it useful for conditions like arthritis. Its anti-inflammatory properties can contribute to overall pain relief.

Appetite Stimulant

CBN could help stimulate appetite. This is particularly beneficial for patients undergoing chemotherapy. It offers an alternative to THC, which also increases appetite but comes with psychoactive effects.

Antibacterial Properties

CBN has been found to have antibacterial properties. It might be effective against antibiotic-resistant bacteria. This could have significant implications for the treatment of bacterial infections.

Neuroprotective Effects

CBN may offer neuroprotective benefits. Research indicates it could help in conditions like Alzheimer’s disease. It might slow down the progression of neurodegenerative diseases.


CBN might help reduce intraocular pressure, making it a potential treatment for glaucoma. Patients could benefit from an alternative to traditional medications.


CBN shows promise as an anti-convulsant. It could help manage epilepsy and other seizure disorders. Further research is needed, but early results are encouraging.

Other Potential Benefits

  • Bone Healing: CBN might aid in bone healing and growth.
  • Psoriasis: It could help manage skin conditions like psoriasis.
  • Cancer: Early studies suggest CBN might have anti-tumor effects.

Summary of Medical Applications

Medical ApplicationPotential Benefits
Sleep AidImproved sleep quality
Pain ReliefChronic pain management
Anti-InflammatoryReduced inflammation
Appetite StimulantIncreased appetite
Antibacterial PropertiesEffective against resistant bacteria
Neuroprotective EffectsSlows neurodegenerative diseases
GlaucomaReduces intraocular pressure
Anti-ConvulsantManages epilepsy
Bone HealingAids in bone growth
PsoriasisManages skin conditions
CancerAnti-tumor effects

CBN offers various potential medical applications. While more research is needed, its benefits are already becoming evident.

Production and Extraction Methods

Producing and extracting Cannabinol (CBN) involves several steps. Understanding these methods can help ensure high-quality output. Let’s dive into the key techniques.

Production of CBN

  1. Aging THC: CBN naturally forms as THC ages. This process can take months or even years. Producers often speed up this process with heat or sunlight.
  2. Synthetic Production: Some labs create CBN synthetically. This method involves chemical reactions and specialized equipment.
  3. Biosynthesis: Using genetically modified organisms (GMOs) to produce CBN. This method is still under research but shows promise.

Extraction Methods

Extracting CBN requires isolating it from cannabis plants. Here are the main techniques:

  • CO2 Extraction: Uses carbon dioxide under high pressure and low temperature to pull cannabinoids from the plant. This method is efficient and safe.
  • Ethanol Extraction: Involves soaking the plant in ethanol. The solvent dissolves cannabinoids, which are then separated and purified.
  • Hydrocarbon Extraction: Uses solvents like butane or propane. This method is quick but requires careful handling due to flammability.

Comparison Table

CO2 ExtractionSafe, efficient, high purityExpensive equipment
Ethanol ExtractionCost-effective, easy to scalePotential for residual solvent
Hydrocarbon ExtractionFast, effectiveFlammable, requires purging

Choosing the Right Method

Selecting the best method depends on several factors:

  • Cost: Budget constraints may limit options.
  • Scale: Larger operations might prefer methods that are easy to scale up.
  • Purity Needs: High-purity products may require more sophisticated techniques.
  • Safety: Methods involving flammable solvents need extra precautions.


Each production and extraction method has its own benefits and drawbacks. Producers should consider their specific needs and capabilities when choosing the best approach.

Market Trends

The market for Cannabinol (CBN) is heating up. More consumers are looking for alternatives to traditional cannabinoids like CBD and THC. This shift in demand has opened new opportunities for CBN.

Rising Popularity

In recent years, CBN has gained attention for its potential health benefits. Consumers are increasingly interested in its:

  • Sleep aid properties
  • Pain relief
  • Anti-inflammatory effects

Investment Surge

Investors are taking note. Companies are pouring money into research and development. The goal is to create high-quality CBN products that meet consumer needs.

Product Innovation

Brands are innovating with CBN in various forms:

  • Tinctures
  • Capsules
  • Edibles
  • Topicals

These new products are making CBN more accessible to a wider audience.

Market Growth

The CBN market is projected to grow rapidly. Here’s a quick look at the numbers:

YearMarket Size (USD)
202150 million
202280 million
2023120 million


Despite the growth, the CBN market faces challenges:

  1. Regulatory hurdles
  2. Limited consumer awareness
  3. High production costs

Companies need to navigate these issues to succeed.


The future looks bright for CBN. As research continues, we can expect:

  • More product variety
  • Lower prices
  • Increased consumer trust

CBN is well on its way to becoming a major player in the cannabinoid market. Keep an eye on this exciting trend.

Potential Side Effects

CBN, like other cannabinoids, comes with its own set of potential side effects. While research is still ongoing, some users have reported the following:

  • Drowsiness: One of the most common side effects. CBN is often touted for its sedative properties, which can be a boon for those with sleep issues but may lead to unwanted daytime drowsiness.
  • Appetite Changes: Some users experience an increase in appetite, known as the “munchies.” This effect is similar to other cannabinoids like THC.
  • Dry Mouth: Commonly referred to as “cottonmouth,” this side effect involves a dry feeling in the mouth and throat.
  • Dizziness: Some individuals report feeling lightheaded or dizzy, particularly when taking higher doses.

Less Common Side Effects

  • Nausea: Though rare, some users might experience stomach discomfort or nausea.
  • Mood Changes: Alterations in mood, either positive or negative, can occur. It’s less common but worth noting.

Interaction with Other Medications

It’s important to consider how CBN interacts with other medications. Cannabinoids can enhance or inhibit the effectiveness of certain drugs. Always consult a healthcare provider before starting any new supplement, especially if you’re on medication.

Individual Variability

Cannabinoids affect everyone differently. Factors like body weight, metabolism, and individual tolerance levels play a role in how CBN impacts each person. What works for one may not work for another, so start with a low dose to gauge your body’s response.

Usage Recommendations

  • Start Low: Begin with a small dose to see how your body reacts.
  • Monitor Effects: Keep track of any side effects or benefits you experience.
  • Consult Professionals: Always seek advice from a healthcare provider, especially if you have underlying health conditions or are taking other medications.

Understanding the potential side effects helps you make informed decisions about incorporating CBN into your wellness routine.

Comparison with Other Cannabinoids


Cannabinol (CBN) and cannabidiol (CBD) both come from the cannabis plant. But they have different effects and uses.

  • Origin: CBD is directly extracted from hemp or cannabis. CBN forms when THC ages and breaks down.
  • Effects: CBD doesn’t cause a high. It’s known for its calming and anti-inflammatory properties. CBN has mild psychoactive effects but is mainly valued for its potential sedative properties.
  • Uses: CBD is popular for anxiety, pain relief, and epilepsy. CBN is gaining attention for sleep aid and possibly stimulating appetite.


Tetrahydrocannabinol (THC) is the well-known compound responsible for the high from cannabis. CBN and THC share some similarities but also have key differences.

  • Psychoactivity: THC is highly psychoactive. CBN has much milder psychoactive effects.
  • Legal Status: THC is illegal in many places due to its psychoactive effects. CBN is typically legal since it’s less psychoactive.
  • Medical Benefits: THC helps with pain, muscle spasticity, glaucoma, insomnia, and low appetite. CBN offers potential benefits for sleep and inflammation without the intense high.


Cannabigerol (CBG) is another minor cannabinoid with growing interest. Comparing CBN to CBG highlights their distinct roles.

  • Formation: CBG is the precursor to other cannabinoids, including THC and CBD. CBN is a derivative of THC.
  • Effects: CBG is non-psychoactive and may help with inflammation, pain, and bacterial infections. CBN is slightly psychoactive and is noted for its potential to aid sleep and relaxation.
  • Availability: CBG is present in small amounts in the cannabis plant. CBN results from the breakdown of THC over time.

CBN in the Spotlight

CBN is emerging as a unique cannabinoid with specific benefits. While it shares some traits with CBD, THC, and CBG, its potential for sleep aid and mild psychoactive effects set it apart. Keep an eye on CBN as further research may unlock more of its benefits and applications.

Future Research and Development

CBN shows promise, but more research is needed to unlock its full potential. Scientists and researchers are diving deeper into its properties and benefits. Here are some key areas of focus:

  • Therapeutic Potential
    Researchers are exploring CBN’s potential in treating various conditions. Early studies suggest it might help with insomnia, pain relief, and anti-inflammatory effects.
  • Extraction and Synthesis
    Efficient extraction methods are essential. Developing cost-effective and scalable methods can make CBN more accessible. Synthetic CBN production is also being investigated.
  • Clinical Trials
    More human trials are necessary to validate CBN’s efficacy and safety. These trials will pave the way for medical applications and regulatory approval.
  • Regulatory Landscape
    Understanding and navigating the legal framework is crucial. As more data becomes available, regulations may evolve, impacting CBN’s market potential.

Current Studies and Findings

Study AreaFindings
Sleep DisordersPotential to improve sleep quality
Pain ManagementPossible analgesic properties
Anti-inflammatoryShows promise in reducing inflammation
NeuroprotectiveEarly signs it may protect brain health

Future Directions

  1. Combination Therapies
    Exploring how CBN works with other cannabinoids could enhance its therapeutic effects.
  2. Product Development
    Creating new CBN-infused products such as oils, edibles, and topicals. Innovation in this space could drive consumer interest.
  3. Public Awareness
    Educating the public about CBN’s benefits and uses will be crucial. Increased awareness can lead to higher demand and more research funding.

Challenges Ahead

  • Regulatory Hurdles
    Navigating complex regulations can slow down development.
  • Market Competition
    With many cannabinoids emerging, CBN must prove its unique benefits to stand out.
  • Funding and Resources
    Securing adequate funding for extensive research is essential. Collaboration between private and public sectors could accelerate progress.


The future of CBN research and development looks promising. Continued efforts in these areas will be key to unlocking its full potential and bringing its benefits to the forefront.


CBN shows immense promise as a high-value cannabinoid. Its unique properties and potential health benefits make it a strong contender for widespread use. Consumers and researchers alike show growing interest in its applications, from sleep aid to pain relief.

The future of CBN looks bright. As more studies emerge, its role in the wellness industry will likely expand. Embracing this cannabinoid could lead to innovative products and new opportunities in the market. Stay tuned, as CBN might soon become a household name.







Editorial Staff

The CannaBizCentral Editorial Team is dedicated to providing a professional, unbiased source for legal cannabis business resource news. With over a decade of experience reporting on the latest cannabis news, we’re committed to meeting the high demand for honest, up-to-date information from the nation’s fastest-growing industry - legal cannabis.